Derivatization reagents for GC, silylation, TSIM

MACHEREY‑NAGEL

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TSIM is the strongest hydroxyl silylator, a reagent of choice for carbohydrates and most steroids (even highly hindered steroids). These products contain harmful substances which must be specially labeled as hazardous. For detailed information please see SDS.

Selling unit 1x10 mL, 5x10 mL, 20x1 mL
Method Gas chromatography (GC), derivatization
Composition N-Trimethylsilyl-imidazole (TSIM)
Derivatization type Silylation
Recommended application(s) Alcohols, Carbohydrates, Derivatization, Glycols, Hormones, Narcotics, Nucleotides, Organic acids, Phenols, Steroids
Storage temperature 2–8 °C / 36–46 °F
Hazardous material Yes

 

DANGER
H225 Highly flammable liquid and vapour.H315 Causes skin irritation.H319 Causes serious eye irritation.H335 May cause respiratory irritation.H360 May damage fertility or the unborn child.
P201 Obtain special instructions before use.P202 Do not handle until all safety precautions have been read and understood.P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking.P233 Keep container tightly closed.P240 Ground/bond container and receiving equipment.P241 Use explosion-proof [electrical/ventilating/lighting] equipment.P242 Use non-sparking tools.P243 Take precautionary measures against static discharge.P261 Avoid breathing dust/fume/gas/mist/vapours/spray.P264 Wash hands thoroughly after handling.P264 Wash hands thoroughly after handling.P271 Use only outdoors or in a well-ventilated area.P280 Wear protective gloves/protective clothing/eye protection/face protection.P280sh Wear protective gloves/eye protection.P280sh Wear protective gloves/eye protection.P280sh Wear protective gloves/eye protection.P302+352 IF ON SKIN: Wash with plenty of water.P303+361+353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].P304+340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.P308+313 IF exposed or concerned: Get medical advice/attention.P312 Call a POISON CENTER/doctor if you feel unwell.P332+313 If skin irritation occurs: Get medical advice/attention.P337+313 If eye irritation persists: Get medical advice/attention.P362+364 Take off contaminated clothing and wash it before reuse.P370+378 In case of fire: Use suitable extinguisher media to extinguish.P403+233 Store in a well-ventilated place. Keep container tightly closed.P403+235 Store in a well-ventilated place. Keep cool.P405 Store locked up.P405 Store locked up.P501 Dispose of contents/container to regulated waste treatment.P501 Dispose of contents/container to regulated waste treatment.P501 Dispose of contents/container to regulated waste treatment.