Derivatization reagents for GC, silylation, TMCS

MACHEREY‑NAGEL

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A 1 molar solution of TMCS in methanol is suited for the esterification of free carboxylic acids and transesterification of glycerides. TMCS and silyl ether remove water and thus drive the reaction to completion. These products contain harmful substances which must be specially labeled as hazardous. For detailed information please see SDS.

Selling unit 6x50 mL, 20x1 mL
Method Gas chromatography (GC), derivatization
Composition Trimethylchlorosilane (TMCS)
Derivatization type Silylation
Recommended application(s) Derivatization, Esterification of free carboxylic acids, TMCS and silyl ether remove water, Transesterification of glycerides
Storage temperature 2–8 °C / 36–46 °F
Hazardous material Yes

 

DANGER
H225 Highly flammable liquid and vapour.H301 Toxic if swallowed.H312 Harmful in contact with skin.H314 Causes severe skin burns and eye damage.H331 Toxic if inhaled.
P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking.P233 Keep container tightly closed.P240 Ground/bond container and receiving equipment.P241 Use explosion-proof [electrical/ventilating/lighting] equipment.P242 Use non-sparking tools.P243 Take precautionary measures against static discharge.P260 Do not breathe dust/fume/gas/mist/vapours/spray.P260sh Do not breathe dust/vapours.P261sh Avoid breathing dust/vapours.P264 Wash hands thoroughly after handling.P264 Wash hands thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P271 Use only outdoors or in a well-ventilated area.P271 Use only outdoors or in a well-ventilated area.P280 Wear protective gloves/protective clothing/eye protection/face protection.P280 Wear protective gloves/protective clothing/eye protection/face protection.P280sh Wear protective gloves/eye protection.P301+310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.P301+330+331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.P302+352 IF ON SKIN: Wash with plenty of water.P303+361+353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].P303+361+353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].P304+340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.P304+340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.P310 Immediately call a POISON CENTER/doctor.P311 Call a POISON CENTER/doctor.P312 Call a POISON CENTER/doctor if you feel unwell.P330 Rinse mouth.P362+364 Take off contaminated clothing and wash it before reuse.P363 Wash contaminated clothing before reuse.P370+378 In case of fire: Use suitable extinguisher media to extinguish.P403+233 Store in a well-ventilated place. Keep container tightly closed.P403+235 Store in a well-ventilated place.