Derivatization reagents for GC, alkylation, methylation, TMSH

MACHEREY‑NAGEL

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TMSH is used for methylation of fatty acids, because it is just necessary to add the reagent (0.2 M in methanol) to the sample solution. Removal of excess reagent is not required, since in the injector of the gas chromatograph at 250 °C pyrolysis to volatile methanol and dimethylsulfide will occur. Due to the high reactivity, complete derivatization is often obtained at ambient temperature. However, heating (e.g., 10 min at 100 °C) in a closed sample vial may be necessary. These products contain harmful substances which must be specially labeled as hazardous. For detailed information please see SDS.

Selling unit 1x10 mL, 5x10 mL, 10x1 mL, 20x1 mL
Method Gas chromatography (GC), derivatization
Composition Trimethylsulfonium hydroxide (TMSH) in methanol
Derivatization type Alkylation, methylation
Recommended application(s) Chlorophenols, Chlorophenoxycarboxylic acids, Derivatization, Free acids, Lipids, Phenols, Triglycerides
Storage temperature 2–8 °C / 36–46 °F
Hazardous material Yes

 

DANGER
H225 Highly flammable liquid and vapour.H301 Toxic if swallowed.H311 Toxic in contact with skin.H315 Causes skin irritation.H319 Causes serious eye irritation.H331 Toxic if inhaled.H370 Causes damage to organs.
P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking.P233 Keep container tightly closed.P240 Ground/bond container and receiving equipment.P241 Use explosion-proof [electrical/ventilating/lighting] equipment.P242 Use non-sparking tools.P243 Take precautionary measures against static discharge.P260 Do not breathe dust/fume/gas/mist/vapours/spray.P260sh Do not breathe dust/vapours.P261sh Avoid breathing dust/vapours.P264 Wash hands thoroughly after handling.P264 Wash hands thoroughly after handling.P264 Wash hands thoroughly after handling.P264 Wash hands thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P270 Do not eat, drink or smoke when using this product.P271 Use only outdoors or in a well-ventilated area.P271 Use only outdoors or in a well-ventilated area.P280 Wear protective gloves/protective clothing/eye protection/face protection.P280 Wear protective gloves/protective clothing/eye protection/face protection.P280sh Wear protective gloves/eye protection.P280sh Wear protective gloves/eye protection.P301+310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.P302+352 IF ON SKIN: Wash with plenty of water.P302+352 IF ON SKIN: Wash with plenty of water.P303+361+353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].P304+340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.P308+311 IF exposed or concerned: Call a POISON CENTER/doctor.P311 Call a POISON CENTER/doctor.P312 Call a POISON CENTER/doctor if you feel unwell.P330 Rinse mouth.P332+313 If skin irritation occurs: Get medical advice/attention.P337+313 If eye irritation persists: Get medical advice/attention.P361+364 Take off immediately all contaminated clothing and wash it before reuse.P362+364 Take off contaminated clothing and wash it before reuse.P370+378 In case of fire: Use suitable ext