GC column, LIPODEX C, 50 m L, 0.25 mm ID, proprietary df

Capillary columns for GC enantiomer separation. LIPODEX cyclodextrin phases are made of cyclic oligosaccharides consisting of six (α-cyclodextrin), seven (β-cyclodextrin) or eight (γ-cyclodextrin) glucose units bonded through α-1,4-linkages. Regioselective alkylation and/or acylation of the hydroxyl groups leads to lipophilic phases with varying enantioselectivity, which are well suited for chiral analyses. Important advantage - many compounds can be analyzed without derivatization (however, for certain substances enantioselectivity can be favorably influenced by formation of derivatives). A large number of separations have been achieved, however, it is not possible to make a general prediction, which phase could solve a given separation task. Even for compounds with small structural differences or within homologous series the enantiodifferentiation can be quite different.